Services

Epigenetic research platform
Contract support

  1. Design and advise of ad-hoc projects.
  2. Purification of miRNAs and histones for epigenetic
    studies.
  3. Methylation arrays(BS-seq, MeDIP, ChIP-seq, EpiTyper by Sequenom.
  4. NGS studies of circulating miRNAs, lncRNAs, RNAs.
  5. Analysis of PTMs by MS, WB, oxy-2D-TAU techniques.

Epigenetic drugs analysis

  1. In vitro characterization of epigenetic activity of molecules in cellular models.
  2. In vivo assays to evaluate the effect of epigenetics molecules in murine models.

EpiGenetic Biomarkers

  1. Identification of diagnostic, prognostic and treatments monitoring biomarkers.
  2. Support on the interpretation of epigenetic results.

Bioinformatics services

Microarrays and NGS

Quality control

 Normalization

 Differential expression Clustering and Classification Biomarkers

Functional analysis

Epigenetic

ncRNAs

- New ncRNAs

- Targets

- Functional analysis of miRNAs

DNA
Methylation

- BS-Seq

- MeDIP-Seq

Chromatin
analysis

- ChIP-Seq

- ChIP-on-chip

Services Workflow

workflow

 

El proyecto ScoliPro cuyo objetivo principal es validar un nuevo test patentado de diagnóstico de la escoliosis idiopática en adolescentes, ha sido parcialmente financiado por el IVACE en el marco del Programa de preparación de Propuestas para convocatorias H2020, para su preparación y presentación a la Convocatoria SME Instrument Phase 2 (IMAPEA/2018/52).